Vol. XXVI, n.2, 2005 ISSN: 0392-2936



european journal
of gynaecological oncology

an International Journal


Editors-in-Chief
A. Onnis
Montréal (CND)
J.H. Check
Camden, NJ (USA)


Associate Editors
M. Marchetti
Montréal (CND)

Assistant Editor
J. Wilson
San Diego - CA (USA)
Editorial Board
Allen H.H., London, Ontario (Canada)
Anteby S.O., Jerusalem (Israel)
Audet-Lapointe P., Montreal (Canada)
Ayhan A., Ankara (Turkey)
Balat O., Graziantep (Turkey)
Barber H.K., New York, NY (USA)
Basta A., Krakow (Poland)
Bender H.C., Dusseldorf (Germany)
Benedetti Panici P.L., Rome (Italy)
Charkviani T., Tbilisi (Georgia)
Dargent D., Lyon (France)
De Oliveira C.F., Coimbra (Portugal)
Dexeus S. Jr., Barcelona (Spain)
De Palo G., Milan (Italy)
Di Paola G.R.,Buenos Aires (Argentina)
Di Re F., Milan (Italy)
Di Saia P., Orange, CA (USA)
Friedrich M., Luebeck (Germany)
Fuller A.F. Jr., Boston, MA (USA)
Geisler H.E., Indianapolis, IN (USA)
Gerbaulet A., Villejuif (France)
Gorins A., Paris (France)
Heintz A.P.M., Utrecht (The Netherlands)
Ioannidou-Mouzaka L.,Athens (Greece)
Jordan J.A., Birmingham, England (UK)
Karseladze A.I., Moscow (Russia)
Klastersky J., Bruxelles (Belgium)
Kubista E., Vienna (Austria)
Kudelka A.P., Houston, TX (USA)
Maggino T., Padua (Italy)
Markowska J., Poznan (Poland)
Marth C., Innsbruck (Austria)
Massuger Leon F.A.G.,
Nijmegen (The Netherlands)
Menczer J., Savyon (Israel)
Monsonego J., Paris (France)
Pinotti A., São Paulo (Brazil)
Piver S.M., Buffalo, NY (USA)
Rakar S., Ljubljana (Slovenia)
Raju K.S., London, England (UK)
Shepherd J.H., London, England (UK)
Stelmachów J., Warsaw (Poland)
Ungár L., Budapest (Hungary)
Vermorken J.B., Edegem (Belgium)
Vîrtej P., Bucharest (Romania)
Wang P.-H., Taipei (Taiwan)
Winter R., Graz (Austria)
Yokoyama Y., Hirosaki (Japan)

Publishing Organization (M. Morsani):
I.R.O.G. CANADA, Inc. - 4900 Côte St-Luc - Apt # 212 - Montréal, Qué. H3W 2H3 (Canada)
Tel. +514-4893242 - Fax +514-4854513 - E-mail: canlux@mgroup-online.com - www.irog.net

Editorial Office (M. Critelli):
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EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY (ISSN 0392-2936) publishes original peer reviewed works in the fields of female genital cancers and related subjects and also proceedings of gynecologic oncology society meetings all over the world. The Journal is covered by CURRENT CONTENTS, SCISEARCH, RESEARCH ALERT, INDEX MEDICUS, MEDLINE, EMBASE/ Excerpta Medica, CURRENT ADVANCES IN CANCER RESEARCH, BIOSIS.

 

European Journal of Gynaecological Oncology
www.irog.net


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© By I.R.O.G. CANADA INC. - Publisher - Editorial office 4900 Côte St. Luc - Apt. 212 - Montréal Québec H3W 2H3 (Canada) - Tel. (514) 4893242-4893640 -Fax (514) 4854513 - Printed in Italy by “La Garangola” - Via E. Dalla Costa, 6 - 35129 Padua (Italy) - Responsible Director: Prof. Antonio Onnis M.D. - Authorization of Padua’s Court n. 633 - 28-6-1979
   
European Journal of Gynaecological Oncology - Vol. XXVI, n. 2, 2005
 
CONTENTS  
DISTINGUISHED EXPERT SERIES  
The impact of anti HPV vaccination on cervical cancer incidence and HPV-induced cervical lesions: Consequences for clinical management 129
J.A. Brinkman, A.S. Caffrey, L.I. Muderspach, L.D. Roman, W.M. Kast - Los Angeles, CA, USA
Development of cervical cancer is associated with infection with high-risk types of human papillomavirus (HPV) creating a unique opportunity to prevent or treat cervical cancer through anti-viral vaccination strategies.
 
FNAC: Its role, limitations and perspective in the preoperative diagnosis of breast cancer 143
P. Zagorianakou, S. Fiaccavento, N. Zagorianakou, G. Makrydimas, N.J. Agnantis - Ioannina, GREECE
The goal was to assess fine needle breast aspiration as we move from the age of morphologic indicators to cell biology.
 
 
REVIEW ARTICLE  
Management of massive presacral pelvic bleeding in patients with gynecological malignances: Review of the literature 151
D. Wydra, J. Emerich, K. Ciach, A. Marciniak - Gdan´ski, POLAND
The management of massive presacral pelvic bleeding in patients with gynecological malignances is described.
 
 
ORIGINAL ARTICLE  
Thoracic metastases from breast cancer: A single-institution’s experience 155
F.L. Ampil, G.V. Burton, B.D.L. Li, Q. Chu, R.M. Krishnamsetty, G. Caldito - Shreveport, LA, USA
A retrospective study evaluated the outcome of breast cancer patients with thoracic metastases.
 
A case of metastasizing invasive hydatidiform mole. Is less - less good? Review of the literature with regard to adequate treatment 158
A. Honig, L. Rieger, P. Kristen, M. Eck, T. Frambach, A. Tschammler, H. Caffier, J. Dietl - Wuerzburg, GERMANY
A case of a metastasizing invasive hydatidiform mole is described with focus on sufficient and adequate cytostatic treatment with low toxicity.
 
Primary breast lymphoma 163
A.L. Areia, M. Dias, M.M. Alves, C.F. de Oliveira - Coimbra, PORTUGAL
Primary breast lymphoma (PBL) is a rare entity; a high incidence of PBL was seen in our department from 1999 to 2003.
 
Detection of axillary metastases in breast cancer patients using ultrasound and colour Doppler combined with fine needle aspiration cytology 165
S. Lemos, M. Dias, M. Gonçalo, E. Pinto, G. Fernandes, C. Oliveira - Coimbra, PORTUGAL
Evaluation of the diagnostic value of ultrasonography/colour Doppler combined with fine needle aspiration cytology for detection of non-palpable axillary lymph node metastases in breast cancer patients.
 
Lymph node pathway in the spread of endometrial carcinoma 167
T. Jobo, R. Sato, T. Arai, T. Tamura, J. Watanabe, H. Kuramoto - Kitasato, JAPAN
The lymph node spread pathway in endometrial carcinoma consists of a route via the obturator or internal iliac node, para-metrium and PAN.
 
Assessment of ER-a and ER-b expression levels in malicious tumors of the uterine corpus 170
A. Popiela, W. Baranowski, G. Popiela, M. Slomczynska, M. Manowiec, M. Gabrys - Krakow, POLAND
Assessment of estrogen receptor (ER-a and ER-b) expression levels in malicious tumors of the uterine corpus is presented.
 
Effects of dioxin and nutrition on cellular proliferation and dioxin- and estrogen-linked genes in ovarian cancer cell lines 175
S. Takahashi, S. Hirano, N. Ito, T. Tamaya - Gifu, JAPAN
Dioxin can stimulate the proliferation of ovarian cancer cell lines in low serum concentration medium.
 
Lymph node sampling is of prognostic value in early stage epithelial ovarian carcinoma 181
I. Skírnisdóttir, B. Sorbe - Örebro, SWEDEN
Tumor grade and lymph node sampling as part of the primary surgery were found to be significant prognostic factors in the treatment of ovarian carcinoma in FIGO Stages I-II. The prognostic value of surgical staging was evaluated in a series of 113 patients.
 
Nuclear alterations of cells and atypical metaplastic cells in cervical smears are predictive criteria of high-grade cervical intraepithelial neoplasia 186
R.M. Dufloth, S.M. Messias-Silva, L.A. Andrade, C. di Loreto, D.M. Munhoz, L.C. Zeferino - São Paulo, BRAZIL
Identification of the cytomorphological criteria used in the screening of cervical smears that would be more predictive of the grades of cervical intraepithelial neoplasia diagnosed at histological evaluation.
 
Development of endometrial cancer following radiation therapy for cervical carcinoma 191
T. Hagiwara, T. Mori, T. Kaku - Fukuoka, JAPAN
The clinical and histologic findings in five cases of endometrial cancer following radiation for squamous cell carcinoma of the cervix are presented.
 
A retrospective study of 32 borderline ovarian tumours: The experience of a non-specialized centre 196
A. Economou, P. Panagopoulos, I. Koutras, G. Petrakos, S. Karadaglis, C. Karcanis - Piraeus, GREECE
Suboptimal staging remains a major problem during the initial operation in non-specialized centres in gynaecologic malignan-cies.
 
Expression of matrix metalloproteinase-2 in preinvasive and invasive carcinoma of the uterine cervix 199
M.A. Mohamed Nasr, S.B. Ayyad, I.K.I. El-Lamie, M.Y. Mikhail - Cairo, EGYPT
Matrix metalloproteinase-2 is an early marker of tumor progression in cervical neoplasia and its expression may denote a potential risk for invasion and metastasis.
 
Effect of hysterosalpingography on serum cancer antigen (CA-125) levels 203
M. Karaca, A. Göçmen, A. Sari, M.G. Ug? ur - Gaziantep, TURKEY
The hysterosalpingography procedure does not have an effect on serum CA-125 levels.
 
BRCA1 mutation, leptin and estrogen levels in breast cancer patients 205
I. Rzepka-Górska, B. Tarnowski, A. Chudecka-Glaz, B. Górski - Szczecin, POLAND
In postmenopausal BRCA1 mutation carriers, leptin levels were significantly lower and correlated with the body mass index.
 
Epidemiology of hydatidiform mole in Finland, 1975 to 2001 207
M. Loukovaara, E. Pukkala, P. Lehtovirta, A. Leminen - Helsinki, FINLAND
The incidence of hydatidiform mole in Finland follows the same patterns as in other Western countries with no changes in recent decades.
 
Differentiation of benign and malignant adnexal masses: value of a morphologic scoring system 209
S. Topuz, H. Saygili, S. Akhan, E. Yavuz, A. Turfanda, S. Berkman - Istanbul, TURKEY
The value of a morphological scoring system to predict malignancy in 58 adnexal masses using ultrasonography was evaluated.
 
Mondor’s disease of the breast: is there any relation to breast cancer? 213
C. Markopoulos, E. Kouskos, D. Mantas, J. Kakisis, Z. Antonopoulou, K. Kontzoglou, N. Nikiteas - Lesvos Island, GREECE
Mondor’s disease of the breast is a rare disorder appearing as thrombophlebitis of subcutaneous veins of the anteriolateral chest wall. The experience of our Breast Unit in managing such lesions is presented.
 
Cytological analysis of the distension fluid used during diagnostic office hysteroscopies in patients with suspected endometrial pathology 215
D. Gerbaldo, A. Papadia, P. Cristoforoni, P. Lorenzi, E. Fulcheri, N. Ragni - Genova, ITALY
Cytological examination of endometrial cells suspended in the distension fluid used for office hysteroscopy seems to be useful in detecting endometrial atypias.
 
 
CASE REPORTS  
Pelvic retroperitoneal paraganglioma mimicking an ovarian mass 219
E. Kuscu, M. Oktem, D. Eroglu, A. Haberal, B. Bilezikci, B. Demirhan - Ankara, TURKEY
A 75-year-old hypertensive female was referred with a suspected ovarian tumor that, in fact, was a pelvic retroperitoneal para-ganglioma. Preoperative imaging did not allow a definitive diagnosis to be made. Explorative surgery was performed, and a mass that arose from the peritoneum was found obstructing the right ureter. The lesion was excised and the histopathologic diagnosis was paraganglioma.
 
Pancreatic tumor in a pregnant woman: A rare case report 221
M. Gojnic, V. Boskovic, A. Fazlagic, T. Mostic, S. Vidakovic, A. Stefanovic, M. Pervulov, S. Petkovic -Belgrade, SERBIA AND MONTENEGRO
Pancreatic tumor is more common in the male population. The literature data about cases of pancreatic tumor in pregnant women are rare. Our patient was an older primipara in the second trimester of pregnancy. After artificial maturation and surgical delivery, the patient was subjected to surgical therapy immediately after delivery. The patient is still alive but under close monitoring and so far without substitutional gynecological therapy.
 
Primary carcinoma of the fallopian tube mimicking tubo-ovarian abscess 225
F.F. Verit, H. Kafali - Sanliurfa, TURKEY
Carcinoma of the fallopian tube should be considered in the differential diagnosis of acute pelvic peritonitis like a tubo-ovarian abscess.
 
Verrucous carcinoma of the cervix - diagnostic and therapeutic difficulties with regards to HPV status. Case report 227
T. Zbroch, P. Grzegorz Knapp, P.A. Knapp - Bialystok, POLAND
A case report of a rare variant of squamous cell carcinoma of the cervix is presented with attention focused on diagnostic processes and HPV involvement.
 
The use of thumbtacks to stop severe presacral bleeding 233
M. Harma, M. Harma, A. Ozturk, M. Bozer - Ankara, TURKEY
Use of standard size drawing pins (thumbtacks) sterilised and deployed as described in the case report is a simple, effective, readily available and potentially lifesaving technique in severe presacral bleeding.
 
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
Vol. XXVI, Number 2, 2005
ISSN: 0392-2936
I.R.O.G. CANADA, Inc.
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