 European
Journal of Gynaecological Oncology - Vol. XXV, n. 3, 2004 |
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| CONTENTS |
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| DISTINGUISHED EXPERT SERIES |
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| Cervical precancer and cancer, past, present
and future |
269 |
G. De Palo - Milan, ITALY
A history of in situ and invasive carcinomas of the cervix is reported. |
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| REVIEW ARTICLES |
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| Prognostic and therapeutic importance of lymphadenectomy
in gynecological cancers |
279 |
A. Ayhan, H. Çelik, P. Dursun, M. Gultekin, K. Yuce - Ankara,
TURKEY
Prognostic and therapeutic importance of lymphadenectomy in gynecological
cancers discussed in the light of literature. |
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| Successful vaccine immunotherapy. An exciting
novel approach to cancer treatment |
287 |
G. Daskalakis, N. Thomakos, A. Papapanagiotou, T. Liakakos, R.L.
Young, A. Antsaklis - Athens, GREECE
Future prospects will be to increase basic knowledge of immunogenic
tumor antigens to vaccine administration, which will make the cancer
patient develop an immune response able to induce tumor regression.
Clinical trials already under way in patients with malignant diseases
may yield more definitive conclusions. |
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| Book Review |
292 |
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| ORIGINAL ARTICLES |
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| Carcinoma in situ and early breast carcinoma.
Survey of the Portuguese Senology Society on the diagnostic tools
used in Portugal and their evolution between 1985 and 2000 |
293 |
C.F. de Oliveira, V. Rodrigues, H. Gervásio, J. Moura Pereira,
J. Albano, N. Amaral - Coimbra, PORTUGAL
Researched by the Senology Society Portuguese hospitals showed an
appreciable improvement in early diagnosis of breast cancer between
1985 and 2000. |
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| Establishment and characterization of two different
types of new human endometrial adenocarcinoma cell lines (HEC-251
and HEC-265) |
299 |
T. Fujisawa, M. Hamano, H. Hata,Y. Kamata, J. Watanabe, R. Sekimoto,
H. Kuramoto - Kanagawa, JAPAN
Two types of novel cell lines from endometrial carcinoma which express
either p53 or PgR are established. |
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| Clinicopathologic outcomes of laser conization
for high-grade cervical dysplasia |
305 |
L. dos Santos, K. Odunsi, S. Lele - New York, USA
Laser conization is associated with a very low incidence of theraml
artifact and postoperative complications, and a relatively low rate
of persistent disease. |
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| Pathological characteristics of ovarian cancer
occurring after hysterectomy |
308 |
R. Halperin, E. Mordechai, S. Zehavi, D. Schneider - Tel Aviv, ISRAEL
It seems that besides reducing the risk of further ovarian cancer,
hysterectomy also causes a change in the main histological sub-group
of ovarian cancer that develops in patients with previous hysterectomy.
The greatest protective effect was observed for serous ovarian tumors. |
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| Soybean isoflavones inhibit estrogen-stimulated
gene expression in mouse uteri |
311 |
Z. Lian, K. Niwa, J. Gao, K. Tagami, K. Onczi, H. Mori, T. Tamaya
- Gifu-city, JAPAN
Soybean isoflavones inhibit the expression of estrogen-stimulated
c-fos, c-jun, IL-1a and TNF-a in mouse uteri. |
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| Clinical review of 55 cases of malignant ovarian
germ cell tumors |
315 |
V. Zanagnolo, E. Sartori, G. Galleri, B. Pasinetti, U. Bianchi -
Brescia, ITALY
Primary treatment of malignant germ cell tumors is conservative surgery
and the role of adjuvant treatment is cardinal. Most patients retain
normal fertility potential. |
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| Modification of ultrasonographically measured
endometrial thickness after discontinuation of adjuvant therapy with
tamoxifen in postmenopausal breast cancer patients |
321 |
M. Valenzano Menada, A. Papadia, P. Lorenzi, S. Costantini, G.F.
Bertelli, N. Ragni - Cuneo, ITALY
A significant reduction in endometrial thickness after discontinuation
of tamoxifen therapy is demonstrated. It can be attributed to cessation
of the estrogenic tamoxifen side-effects. |
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| Clinicopathological study of vascular tumors
of the breast: a series of ten patients with a long follow-up |
324 |
A. Kondis-Pafitis, J. Psyhogios, H. Spanidou-Carvouni, P. Kairi-Vassilatou,
K. Kontogianni, V. Smyrniotis - Athens, GREECE
Clinicopathological features of ten cases of vascular tumors of the
breast with a long follow-up are described. |
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| First-line intraperitoneal cisplatin-paclitaxel
and intravenous ifosfamide in Stage IIIc ovarian epithelial cancer |
327 |
B. Zylberberg, D. Dormont, P. Madelenat, E. Darai - Cedex, FRANCE
First-line intraperitoneal chemotherapy with paclitaxel-CDDP is effective
in untreated Stage III ovarian cancer patients even with initial unresectable
disease. |
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| Role of plasma nitric oxide in complete hydatidiform
mole |
333 |
M. Harma, M. Harma, A. Kocyigit, N. Demir - Sanliurfa, TURKEY
This is the first report to suggest a risk association between elevated
plasma nitric oxide levels and development of complete hydatidiform
mole. |
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| The significance of the degree of myometrial
invasion in patients with Stage IB endometrial cancer |
336 |
O. Gemer, L. Uriev, T. Harkovsky, R. Peled, D. Ben-Dor, F. Barak,
S. Segal - Ashkelon, ISRAEL
In Stage IB endometrial cancer, myometrial invasion of more than one-third
compared with invasion less than one-third does not affect outcome. |
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| Sentinel node identification and intraoperative
lymphatic mapping. First results of a pilot study in patients with
endometrial cancer |
339 |
N. Fersis, I. Gruber, K. Relakis, M. Friedrich, S. Becker, D. Wallwiener,
U. Wagner - Tuebingen, GERMANY
The identification of sentinel lymph nodes in endometrial cancer is
a practical and safe method. In order to improve this technique as
a standard procedure for staging of endometrial cancer further studies
with a larger number of patients have to be done. |
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| Postoperative radiotherapy in Stage I endometrial
adenocarcinoma |
343 |
V. Kukura, L. Markulin-Grgic´, F. S?antek, G. Zovko, S. Ciglar,
J. Valetic´ - Zagreb, CROATIA
Postoperative whole pelvic radiation demonstrates good results in
patients with high-risk surgical Stage I endometrial adenocarcinoma. |
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| A novel technique with a flexible applicator
for MRI-based brachytherapy of cervical cancer |
347 |
J. Hadjiev, G. Antal, Z. Antalffy, P. Bogner, O. Ésik, I.
Repa - Kaposvár, HUNGARY
Preliminary results with an adjustable applicator technique for magnetic
resonance-based, 3-dimensional high-dose rate brachytherapy for cervical
cancer, resulted in improved dose distribution. |
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| Human chorionic gonadotropin-beta in endometrium
cancer tissue |
351 |
E. Nowak-Markwitz, A. Jankowska, A. Szczerba, M. Andrusiewicz -
Poznan´
The expression of hCG b gene in endometrial cancer tissue was present
in all cases and serum-free hCGb immunoreactivity was a less common
feature. |
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| External radiation therapy for endometrial
carcinoma: The University Hospital of Ioannina experience |
355 |
E.E. Pakos, S.P. Gritzeli, P.G. Tsekeris, E.J. Pitouli, M.E. Fintzou
- Ioannina, GREECE
External radiotherapy alone achieved excellent local control in women
with endometrial carcinoma with satisfactory overall and disease-free
survival. |
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| DNA adducts in squamous cell cervical carcinomas
associated with HPV infection |
359 |
A. Kwas´niewska, A. Goz´dzicka-Józefiak, A. Borze?cki,W.
Baranowski - Lublin, POLAND
The aim of this study was qualitative and quantitative evaluation
of DNA adducts in squamous cell cervical carcinomas associated with
oncogenic HPV infection. The study results suggest that the content
of DNA adduct content in squamous cell cervical cancer associated
with HPV infection may serve as a molecular marker of oncogenesis
in this organ. |
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| Estrogen and progesterone expression of vessel
walls with intravascular leiomyomatosis; Discussion of histogenesis |
362 |
G. Kir,M. Kir,A. Gurbuz, A. Karateke, F. Aker - Istanbul, TURKEY
Estrogen and progesterone expressions of vessel walls with intravascular
leiomyomatosis; discussion of histogenesis. |
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| Survival in primary inoperable breast cancer
patients |
367 |
C. Dimitrakakis, A. Keramopoulos - Athens, GREECE
Neoadjuvant chemotherapy followed by surgery offers a survival advantage
in primary inoperable breast cancer patients. Metastatic and hormonal
receptor status provides additional prognostic information. |
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| Postmenopausal endometrial cancer screening:
is there a correlation between transvaginal sonographic measurement
of endometrial thickness and body mass index? |
373 |
M.A. Güven, Ö. Pata, S. Bakaris, A. Kafkasli, L. Mgoyi
- Kahramanmaras, TURKEY
The correlation of body mass index with transvaginal sonographic measurement
of endometrial thickness in a cohort of postmenopausal women admitted
for endometrial cancer surveillance is reported. |
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| Treatment delay and pathology results in women
with low-grade squamous intraepithelial lesions. A preliminary study |
376 |
G. Iatrakis, G. Kourounis, N. Georgopoulos, J. Karachotzitis - Athens,
GREECE
Prolongation of an observation period > 2 years in women diagnosed
with CIN 1 is a possible alternative approach. |
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| Results of cisplatin, adriamycin and etoposide
chemotherapy in patients with recurrent and metastatic endometrial
cancer |
379 |
T. Bilgin, H. Ozan, H. Filiz Kara - Bursa, TURKEY
A combination treatment of cisplatin, adriamycin and etoposide is
highly active in recurrent or metastatic endometrial cancer. |
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| CASE REPORTS |
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| Recurrent extraperitoneal low grade leiomyosarcoma
with unusual localization |
381 |
E.S. Guvendag Guven, S. Guven, S. Esin, A. Usubutun, D. Akata, A.
Altintas, A. Ayhan - Ankara, TURKEY
Low-grade soft tissue leiomyosarcoma may rarely occur in the paravaginal
space. |
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| Primitive neuroectodermal tumor (PNET) of the
uterine isthmus |
384 |
I.D. Venizelos, M. Zafrakas, K. Dragoumis, P. Tzevelekis, D. Kellartzis,
J. Bontis - Thessaloniki, GREECE
A rare case of a primitive neuroectodermal tumor (PNET) of the uterine
isthmus is presented. |
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| Endometrial involvement by intra-abdominal
diffuse malignant mesothelioma |
387 |
G. Kir, M. Kir, A. Karateke, F. Özkan - Istanbul, TURKEY
This is the first reported case of intra-abdominal diffuse malignant
mesothelioma metastasing to the endomemtrium. |
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| Microscopic endometrioid carcinoma arising
in endosalpingeal endometriosis |
389 |
A. Karateke, G. Kir, A. Gurbuz, F. Aker - Istanbul, TURKEY
Microscopic endometrioid carcinoma arising in endosalpingeal endometriosis
is reported. |
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| Solitary spleen metastasis and amyloidosis
in a patient with endometrial cancer |
391 |
H. Gogas, Th. Ignatiadis, Ch. Markopoulos, S. Karageorgopoulou,
D. Floros, G. Vaiopoulos - Athens, GREECE
A case of solitary spleen metastasis with amyloidosis of the spleen
in a patient with endometrial cancer is presented. |
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| Well-differentiated papillary mesothelioma
complicating endometrial carcinoma: A case report |
394 |
S. Erkanli, E.B. Kilicdag, F. Bolat, F. Kayaselcuk, T. Bagis, A.
Haberal, E. Kuscu - Adana, TUREKY
A case of well-differentiated papillary mesothelioma discovered during
staging surgery for endometrial carcinoma in a 50 year-old postmenopausal
woman is presented. |
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| Letter to the Editor |
397 |
| Book Review |
399 |
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