| Vol. XXV, n. 2, 2004 | ISSN: 0392-2936 |
european journal
of
gynaecological oncology
an International Journal
Editor-in-Chief
| A. Onnis | P. Bösze |
| Montréal (CND) | Budapest (Hungary) |
Associate Editor
M. Marchetti
Montréal (CND)
Assistant Editor
J. Wilson
San Diego - CA (USA)
| Editorial Board | ||
H.H. Allen, London, Ontario (Canada) |
S.K. Fotiou, Athens (Greece) A.F. Fuller Jr., Boston, MA (USA) H.E. Geisler, Indianapolis, IN (USA) A. Gerbaulet, Villejuif (France) A. Gorins, Paris (France) A.P.M. Heintz, Utrecht (The Netherlands) L. Ioannidou-Mouzaka, Athens (Greece) J.A. Jordan, Birmingham, England (UK) A.I. Karseladze, Moscow (Russia) J. Klastersky, Bruxelles (Belgium) V. Kozachenko, Moscow (Russia) B. Kralj, Ljubljana (Slovenia) E. Kubista, Vienna (Austria) A.P. Kudelka, Houston, TX (USA) T. Maggino, Padua (Italy) J. Markowska, Poznan (Poland) C. Marth, Innsbruck (Austria) |
Leon F. A. G. Massuger, Nijmegen (The Netherlands) J. Menczer, Savyon (Israel) J. Monsonego, Paris (France) A. Pinotti, São Paulo (Brasil) S.M. Piver, Buffalo, NY (USA) S. Rakar, Ljubljana (Slovenia) K.S. Raju, London, England (UK) J.H. Shepherd, London, England (UK) P. Sismondi, Turin (Italy) J. Stelmachów, Warsaw (Poland) L. Ungár, Budapest (Hungary) I. Vergote, Leuven (Belgium) J.B. Vermorken, Edegem (Belgium) P. Vîrtej, Bucharest (Romania) P.-H. Wang, Taipei (Taiwan) R. Winter, Graz (Austria) Y. Yokoyama, Hirosaki (Japan) J. Zielinski, Warsaw (Poland) |
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 European
Journal of Gynaecological Oncology - Vol. XXV, n. 2, 2004 |
|
| CONTENTS | |
| DISTINGUISHED EXPERT SERIES | |
| The benefits of haematopoietic growth factors in the management of gynaecological oncology | 133 |
| D.C. Dale - Washington, USA Neutropenia and anemia are important complications of cancer chemotherapy and can be prevented and treated with granulo-cyte colony-stimulating factor and erythropoietin. |
|
| BRIDGING THE GAP | |
| The meaning of the methylation of genomic DNA in the regulation of gene expression levels | 145 |
| A. Popiela, G. Keith, A. Borzecki, G. Popiela, M. Manowiec, M. Gabrys
- Wroclaw, POLAND Recent knowledge concerning the methylation of DNA, which is one of the major epigenetic mechanisms that deactivates genes is presented. |
|
| EDITORIAL ARTICLES | |
| Anti human papillomavirus vaccine: The checkmate to human papillomavirus? | 151 |
| M. Moscarini, A. Lukic, C. Franco - Rome, ITALY The use of prophylactic vaccines could reduce the incidence of HPV infection and, consequently, reduce the incidence of malig-nant and benign HPV-correlated disease. |
|
| Androgens and ovarian cancers | 157 |
| P.H. Wang, C. Chang - Taipei, TAIWAN Much evidence supports the importance of androgens in the initiation or progression of epithelial ovarian cancers. |
|
| ORIGINAL ARTICLES | |
| HSP27 in patients with ovarian carcinoma: still an independent prognostic indicator at 60 months follow-up | 165 |
| J.P. Geisler, J.E. Tammela, K.J. Manahan, H.E. Geisler, G.A. Miller,
Z. Zhou, M.C. Wiemann -Indianapolis, IN (USA) HSP27 is an independent prognostic indicator in patients with ovarian cancer. |
|
| Are nodal metastases in ovarian cancer chemoresistant lesions? Analysis of nodal involvement in 105 patients treated with preoperative chemotherapy | 169 |
| P. Morice, F. Joulie, A. Rey, D. Atallah, S. Camatte, P. Pautier,
A. Thoury, C. Lhommé, P. Duvillard, D. Castaigne - Villejuif, FRANCE The rates of nodal involvement seem to be similar in patients treated before or after chemotherapy. Such results suggest that nodal metastases are chemoresistant lesions. |
|
| Influence of stroma-derived growth factors on the estradiol-stimulated proliferation of human breast cancer cells | 175 |
| H. Seeger, D. Wallwiener, A.O. Mueck - Tuebingen, GERMANY Stroma-derived growth factors can enhance the estradiol-induced proliferation of human breast cancer cells. |
|
| Detection of the sentinel lymph node under local anaesthesia in early-stage breast cancer: Feasibility study in a series of 78 unselected patients | 178 |
| Y. Aubard, J. Mollard, T. Ducloux, J. Monteil, V. Fermeaux, M. Desfougères,
J. Gana, E. Serdouma - Limoges, FRANCE It is feasible to detect the sentinel lymph node under local anaesthesia in an unselected population. Using this procedure, patients can undergo surgery with the knowledge of their axillary lymph node status while at the same time avoiding the uncer-tainties of an intraoperative examination of the sentinel lymph node - a source of many false negatives, particularly in the event of micrometastases. |
|
| An analysis of different approaches to ovarian cysts in Italy | 183 |
| C. Romagnolo, T. Maggino, P. Zola, E. Sartori, A. Gadducci, F. Landoni
- Milan, ITALY Answers to a questionnaire on the diagnostic triage and therapeutic options of pelvic masses in Italy were analyzed; members of the Italian Society of Gynecological Oncology and the Italian Society of Gynecologic Endoscopy were interviewed. |
|
| Clinical implications of insulin-like growth factors through the presence of their binding proteins and recep-tors expressed in gynecological cancers | 187 |
| S. Hirano, N. Ito, S. Takahashi, T. Tamaya - Gifu, JAPAN The abnormally balanced co-expression of IGFBPs and IGF-R might be involved in the growth of gynaecological cancers. |
|
| The role of leptin in breast cancer | 192 |
| A. Markowska, K. Malendowicz, K. Drews - Poznan, POLAND A number of studies indicate a relation between leptin levels and breast cancer. Leptin may become a prognostic factor in this cancer. |
|
| Paclitaxel/carboplatin versus cyclophosphamide/carboplatin in peritoneal carcinomatosis of the ovary | 195 |
| O. Balat - Gaziantep, TURKEY Paclitaxel/carboplatin increases the rate of optimal debulking in peritoneal carcinomatosis of the ovary compared to carbopla-tine/ cyclophosphamide. |
|
| Transvaginal laparoscopy proposed as an investigation procedure for patients at high-risk for ovarian cancer | 197 |
| V. Tanos - Nicosia, CYPRUS Transvaginal laparoscopy, a minimally invasive technique, is proposed to investigate high-risk ovarian cancer patients to rule out ovarian cancer. |
|
| Ovarian masses in young adolescents: imaging findings with surgical confirmation | 201 |
| V.T. Skiadas, V. Koutoulidis, M. Eleytheriades, A. Gouliamos, L.A.
Moulopoulos, E. Deligeoroglou, L. Vlachos, G. Kreatsas - Athens, GREECE The clinical features, radiologic and pathologic findings of 37 female adolescents who were operated on in our hospital for an ovarian mass are presented. |
|
| The role of transvaginal ultrasonography and serum CA 125 assay combined with age and hormonal state in the differential diagnosis of pelvic masses | 207 |
| A. Mancuso, A. De Vivo, O. Triolo, S. Irato - Messina, ITALY CA 125 and transvaginal echography have a higher efficacy in diagnosing ovarian malignancy if they are associated with age and hormonal state. |
|
| The efficacy of intravenous versus epidural tramadol with patient-controlled analgesia (PCA) in gyneco-logic cancer pain | 211 |
| G. Kir, M. Kir, H. Cetiner, A. Karateke, A. Gurbuz - Istanbul, TURKEY Diagnostic problems on frozen section examination of myometrial invasion in patients with endometrial carcinoma; with special emphasis on the pitfalls of deep adenomyosis with carcinomatous involvement. |
|
| The efficacy of intravenous versus epidural tramadol with patient-controlled analgesia (PCA) in gynecologic cancer pain | 215 |
| L. Yavuz, F. Eroglu, M. Ozsoy - Isparta, TURKEY Epidural administration of tramadol through a patient-controlled analgesia method following gynecologic cancer surgery was found to be a more effective analgesia in lower doses when compared to intravenous administration. |
|
| Angiogenic properties of carcinoma in situ and microinvasive carcinoma of the uterine cervix | 219 |
| M. Sotiropoulou, E. Diakomanolis, A. Elsheikh, D. Loutradis, S.
Markaki, S. Michalas - Athens, GREECE The process of neoangiogenesis in normal squamous cell epithelium, and dysplastic and micro-invasive carcinoma of the uterine cervix was studied. |
|
| The incidence of female genital tumors in the province of Sassari in the period 1992-2000 | 222 |
| E. Kairi-Vassilatou, K. Kontogianni, M. Salamalekis, K. Sykiotis,
A. Kondi-Pafitis - Athens, GREECE The aim of this study was to investigate the relationship, if any, among adenomyosis, endometrial adenocarcinoma, hyperplasia and leiomyomas. The frequent coexistence of adenomyosis and other hormone-dependent uterine lesions is strongly suggestive of the presence of a common hormonal factor in the pathogenesis. |
|
| The prognostic significance of the immunohistochemical expression of p53, bcl-2, c-erb B-2 and cathep-sin D in ovarian cancer patients receiving platinum with cyclophosphamide or paclitaxel chemotherapy | 225 |
| A. Protopapas, E. Diakomanolis, A. Bamias, S. Milingos, S. Markaki,
C. Papadimitriou, A.-M. Dimopoulos, S. Michalas - Athens, GREECE Paclitaxel-based combinations improve survival in ovarian cancer patients possibly due to their plethoric apoptotic action which eliminates chemoresistant populations of p53 and cathepsin-D overexpressing cells. |
|
| Missed cancers on mammograms: Causes and measures of prevention | 230 |
| E. Kouskos, C. Markopoulos, D. Mantas, K. Revenas, Z. Antonopoulou,
K. Kontzoglou, J. Gogas - Athens, GREECE Mammographically missed cancers are not uncommon, are related to delayed diagnosis and treatment, and present an increasing legal aspect associated to malpractice ligitation. |
|
|
|
| CASE REPORTS | |
| Solitary splenic metastasis of endometrial carcinoma ten years after hysterectomy. Case report and review of the literature | 233 |
| C. Hadjileontis, I. Amplianitis, C. Valsamides, G. Harisis, H. Nepka,
A. Kafanas - Serres, GREECE Carcinomatous metastases at the spleen are rare and usually appear with generalized carcinomatosis. A case with solitary splenic involvement ten years after hysterectomy is presented. |
|
| Hyperplastic mesothelial cells in pelvic and abdominal lymph node sinuses mimicking metastatic ovarian microinvasive serous borderline tumor | 236 |
| G. Kir, S. Eren, M. Kir - Istanbul, TURKEY Hyperplastic mesothelial cells in pelvic and abdominal lymph node were encountered in the staging procedure of a 32-year-old woman with a left ovarian microinvasive serous borderline tumor. |
|
| Primary ovarian small cell carcinoma of the pulmonary type: A case report and review of the literature | 239 |
| J. Mebis, H. De Raeve, M. Baekelandt, W.A.A. Tjalma, J.B. Vermorken
- Edegem, BELGIUM A case of a 54-year-old woman with both a Stage IIIC small cell carcinoma, pulmonary type, and a well-differentiated endometrioid adenocarcinoma of the left ovary in combination with a Brenner tumor in the right ovary is reported. |
|
| Cellular angiofibroma of the vulva: Report of a case | 242 |
| Y. Dikmen, M.S. Yucebilgin, M. Kazandi, O. Zekioglu, T. Akalin,
N. Ozdemir - Izmir, TURKEY Cellular angiofibroma of the vulva is a benign mesenchymal tumor, a lesion that should be considered in the differential diagnosis of vulvar soft tissue tumors. |
|
| Vaginal bleeding as a first symptom of malignant lymphoma: Case reports, diagnosis and successful treatment | 245 |
| J. Sobotkowski, M. Blasin´ska-Morawiec, I. Dowgier-Witczak
- Lodz, POLAND Three cases of malignant lymphoma at an uncommon, gynaecological site are described. Chemotherapy, radiotherapy (tele-and brachytherapy) were performed with good, long-term results. |
|
| Long-lasting complete remission of a patient with cervical cancer FIGO IVB treated by concomitant chemobrachyradiotherapy with ifosfamide and cisplatin and consolidation chemotherapy - a case report | 247 |
| E. Vrdoljak, W. Hamm, T. Omrc?en, T. Prskalo - Split, CROATIA A case report of a patient with locally advanced cervical cancer with an isolated metastasis to the left ovary treated by chemoradiation is presented. |
|
| Subcutaneous metastasis of endometrial adenocarcinoma: Case report of an incidental diagnosis during abdominal sonography | 250 |
| Y. Dikmen, M.C. Terek, L. Mgoyi, O. Zekioglu, F. Akercan, M.S. Yucebilgin
- Izmir, TURKEY A rare case of subcutaneous metastasis from endometrial adenocarcinoma detected incidentally on the anterior abdominal wall during routine abdominal sonography is reported. |
|
| Angiomyofibroblastoma of the vulva: report of a case | 253 |
| F. Montella, M. Giana, A. Vigone, D. Surico, N. Surico - Novara,
ITALY Angiomyofibroblastoma of the vulva is a rare entity and only a few cases have been reported in the literature. The rarity of cases can lead to a misdiagnosis by pathologists and gynaecologists. A case of solitary angiomyofibroblastoma of the vulva in a 16-year-old woman was examined by histology and immunohisto-chemistry. |
|
| Endometrioid adenocarcinoma arising in endometriosis foci six years after estrogen replacement therapy: a case report | 255 |
| A. Areia, V. Sousa, C. Frutuoso, I. Dias, M.I. Martins, C.F. de
Oliveira - Coimbra, PORTUGAL A case of an endometrial adenocarcinoma arising in endometriosis foci in a patient on estrogen hormone replacement treatment is presented. |
|
| Subcutaneous metastasis of endometrial adenocarcinoma: Case report of an incidental diagnosis during abdominal sonography | 257 |
| E. Kostopoulou, A. Moulla, D. Giakoustidis, M. Leontsini - Thessaloniki,
GREECE Cases of sclerosing stromal tumors were examined by immunohistochemistry and fluorescence in situ hybridization. |
|
| Pregnancy associated breast cancer: A case report | 261 |
| P.V. Ginopoulos, G.D. Michail, G.S. Kourounis - Patras, GREECE A pregnant woman with invasive ductal breast carcinoma treated with combined surgery, chemotherapy and radiotherapy responded well without fetal problems. |
|
Vol. XXV, Number 2, 2004
ISSN: 0392-2936
I.R.O.G. CANADA, Inc.
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