Vol. XXVII, n.5, 2006 ISSN: 0392-2936


european journal
of gynaecological oncology

an International Journal


Editors-in-Chief
A. Onnis
Montréal (CND)
P. Bösze
Budapest (Hungary)


Associate Editors
M. Marchetti
Montréal (CND)

Assistant Editor
J. Wilson
San Diego - CA (USA)
Editorial Board
Allen H.H., London, Ontario (Canada)
Anteby S.O., Jerusalem (Israel)
Audet-Lapointe P., Montreal (Canada)
Ayhan A., Ankara (Turkey)
Balat O., Graziantep (Turkey)
Barber H.K., New York, NY (USA)
Basta A., Krakow (Poland)
Bender H.C., Dusseldorf (Germany)
Benedetti Panici P.L., Rome (Italy)
Charkviani T., Tbilisi (Georgia)
De Oliveira C.F., Coimbra (Portugal)
Dexeus S. Jr., Barcelona (Spain)
Di Paola G.R.,Buenos Aires (Argentina)
Di Re F., Milan (Italy)
Di Saia P., Orange, CA (USA)
Fuller A.F. Jr., Boston, MA (USA)
Geisler H.E., Indianapolis, IN (USA)
Gerbaulet A., Villejuif (France)
Gorins A., Paris (France)
Heintz A.P.M., Utrecht (The Netherlands)
Ioannidou-Mouzaka L.,Athens (Greece)
Jordan J.A., Birmingham, England (UK)
Karseladze A.I., Moscow (Russia)
Klastersky J., Bruxelles (Belgium)
Kubista E., Vienna (Austria)
Kudelka A.P., Houston, TX (USA)
Maggino T., Padua (Italy)
Markowska J., Poznan (Poland)
Marth C., Innsbruck (Austria)
Massuger Leon F.A.G.,
Menczer J., Savyon (Israel)
Monsonego J., Paris (France)
Pinotti A., São Paulo (Brazil)
Piura B., Beer Sheva (Israel)
Piver S.M., Buffalo, NY (USA)
Rakar S., Ljubljana (Slovenia)
Raju K.S., London, England (UK)
Shepherd J.H., London, England (UK)
Stelmachów J., Warsaw (Poland)
Tjalma W., Antwerpen (Belgium)
Ungár L., Budapest (Hungary)
Vermorken J.B., Edegem (Belgium)
Vîrtej P., Bucharest (Romania)
Wang P.-H., Taipei (Taiwan)
Winter R., Graz (Austria)
Yokoyama Y., Hirosaki (Japan)

Publishing Organization (M. Morsani):
I.R.O.G. CANADA, Inc. - 4900 Côte St-Luc - Apt # 212 - Montréal, Qué. H3W 2H3 (Canada)
Tel. +514-4893242 - Fax +514-4854513 - E-mail: canlux@mgroup-online.com - www.irog.net

Editorial Office (M. Critelli):
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EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY (ISSN 0392-2936) publishes original peer reviewed works in the fields of female genital cancers and related subjects and also proceedings of gynecologic oncology society meetings all over the world. The Journal is covered by CURRENT CONTENTS, SCISEARCH, RESEARCH ALERT, INDEX MEDICUS, MEDLINE, EMBASE/ Excerpta Medica, CURRENT ADVANCES IN CANCER RESEARCH, BIOSIS.

 

European Journal of Gynaecological Oncology
www.irog.net


General Information

The EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY (ISSN 0392-2936) publishes original peer reviewed work, preferably brief reports, in the fields of female genital cancers and related subjects – prevention, early detection, epidemiology, pathology, diagnosis, management – and also proceedings of Gynaecologic Oncology Society meetings all over the world.

The Journal is covered by CURRENT CONTENTS, SCISEARCH, RESEARCH ALERT, INDEX MEDICUS, MEDLINE,
EMBASE/ Excerpta Medica, CURRENT ADVANCES IN CANCER RESEARCH, BIOSIS.

AIMS AND SCOPE
The EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY is dedicated to publishing editorial articles in the “Distin-guished Expert Series” and original research papers, case reports, letters to the Editor, book reviews and newsletters.

The Journal was founded in 1980 – the second gynaecologic oncology hyperspecialization journal in the world. Its aim is the dif-fusion of scientific, clinical and practical progress and knowledge in female neoplastic diseases in an interdisciplinary approach among gynaecologists, oncologists, radiotherapists, surgeons, chemotherapists, pathologists, epidemiologists and so on.

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European Journal of Gynaecological Oncology
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© By I.R.O.G. CANADA INC. - Publisher - Editorial office 4900 Côte St. Luc - Apt. 212 - Montréal Québec H3W 2H3 (Canada) - Tel. (514) 4893242-4893640 - Fax (514) 4854513 - Printed in Italy by “La Garangola” - Via E. Dalla Costa, 6 - 35129 Padua (Italy) - Responsible Director: Prof. Antonio Onnis M.D. - Authorization of Padua’s Court n. 633 - 28-6-1979
   
European Journal of Gynaecological Oncology - Vol. XXVII, n. 5, 2006
 
   
CONTENTS  
DISTINGUISHED EXPERT SERIES  
Ovulatory failure, fertility preservation and reproductive strategies in the setting of gynecologic and non-gynecologic malignancies 449
K.S. Tewari, P.J. Di Saia - Orange, CA, USA  
 
ORIGINAL ARTICLES  
Number and distribution of pelvic lymph nodes and effect of surgical pathologic factors on pelvic lymph node status in patients with early-stage cervical carcinoma treated with radical hysterectomy and pelvic lymph node dissection 463
B. Piura, A. Rabinovich, M. Friger - Beer-Sheva, ISRAEL In surgically treated cervical carcinoma cases the mean number of removed pelvic nodes per patient was 26.6. Positive nodes were found in 30.7% of the patients with a mean of 3.4 positive nodes per patient. Positive lymph vascular space invasion was the strongest predictor of positive pelvic lymph nodes.  
Do risk factors for epithelial ovarian cancer have an impact on prognosis? Focus on previous pelvic surgery and reproductive variables 467
A. Kjærbye-Thygesen, K. Frederiksen, E.V. Høgdall, C.K. Høgdall, J. Blaakær, S. Krüger Kjær - Aarhus, DENMARK
Previous pelvic surgery and increasing number of lifetime ovulation-years were associated with respectively improved and decreased survival of patients with epithelial ovarian cancer Stage III.
 
Telomerase activity and the subunit of telomerase in hydatidiform mole and their relationship with the development of postmolar tumor 473
F.Wang, H. Huang, X. Kang, B. Chen, Y. Li - Zhanjiang, PEOPLE’S REPUBLIC OF CHINA For gestational trophoblastic diseases telomerase activity is associated with serum hCG levels but is not related to other clinical risk factors.  
Influence of diabetes mellitus and nodal distribution in endometrial cancer and correlation to clinicopathological prognostic factors 477

E. Steiner, M. Schmidt, W. Weikel, H. Koelbl - Ludwigshafen, GERMANY The relationships between the distribution of nodal disease, clinico-pathological patterns and recurrence and survival in surgically staged cases of endometrial cancer are described.

 
Prognostic significance of fascin expression in endometrioid carcinoma 481
S. Kabukcuoglu, U. Oner, S.S. Ozalp, E. Dundar, O.T. Yalcin, E. Colak - Eskisehir, TURKEY The dynamic role of actin bundling protein fascin in generating and maintaining endometrial neoplasms is considered.  
Preoperative diagnosis of 221 consecutive ovarian masses: scoring system and expert evaluation 487
C. Romagnolo, G. Trivella, M. Bonacina, M. Fornalè, T. Maggino, E. Ferrazzi - Milan, ITALY In the diagnosis of pelvic masses, an easy sonographic descriptive scoring system is not significantly lower in accuracy than the expertise achieved by a gynaecologist with sonographic skills.  
Expression of the epidermal growth factor system in endometrial cancer after adjuvant tamoxifen treatment for breast cancer 490
G. Androutsopoulos, G. Adonakis, M. Gkermpesi, P. Gkogkos, P. Ravazoula, G. Kourounis - Rion, GREECE Endometrial cancer after tamoxifen treatment: a clinicopathologic study.  
Analysis of the relationship between cancer procoagulant activity and PCNA and Ki-67 expression in cases of common and cellular uterine leiomyomas 495
Slawomir D. Szajda, Marcin Józ´wik, Mariola Sulkowska, Ewa Chabielska, Stanislaw Sulkowski, Maciej Józ´wik - Bialystok, POLAND Cellular leiomyomas do not differ in the serum or the intratumor CP activity from common leiomyomas, whereas there is a relationship of intratumor CP activity with PCNA expression.  
CD24 expression is a poor prognostic marker in endometrial carcinoma 500
N. Karahan, M. Güney, B. Oral, N. Kapucuoglu, T. Mungan - Isparta, TURKEY CD24 expression in endometrial carcinoma as detected by immunohistochemistry might be a new marker for a more aggressive endometrial cancer biology.  
Endometrial carcinoma and diabetes revisited 505
N. Papanas, A. Giatromanolaki, G. Galazios, E. Maltezos, E. Sivridis - Alexandroupolis, GREECE Diabetic patients with endometrial carcinoma do not differ from non-diabetic patients in tumor characteristics, clinical risk factors and survival.  
 
CASE REPORTS  
Malignant mixed Müllerian tumor with heterologous component arising in the fallopian tube - a case report 509
G. Hudelist, K. Unterrieder, O. Kandolf, G. Alpi, S. Pucher, G. Pollak, K. Czerwenka, J. Keckstein - Vienna, AUSTRIA
Primary malignant mixed Müllerian tumors (MMMT) of the fallopian tube are extreme rarities in gynecologic oncology. A case of FIGO Stage II primary fallopian MMMT with heterologous tumor portion is reported.
 
A new approach to treatment of early-stage cervical carcinoma: entire laparoscopic abdominal radical hysterectomy with bilateral pelvic lymphadenectomy without vaginal cuff closure - case reports 513
B. Sert, V.M. Abeler, A. Dørum, C.G. Trope - Oslo, NORWAY A new technique of laparoscopic radical hysterectomy without vaginal cuff closure is described.  
Gorlin syndrome associated with basal cell carcinoma of the vulva: A case report 519
M. Giuliani, L. Di Stefano, G. Zoccali, E. Angelone, P. Leocata, G. Mascaretti - L’Aquila, ITALY Gorlin syndrome, linked to PTCH gene mutation, can be transmited by parents or can occur spontaneously.  
Refractory metastatic choriocarcinoma treated surgically with polychemotherapy - case report 523
M. Petronijevic, S. Vrzic-Petronijevic, V. Boskovic, D. Bratic, Lj. Vicovac, M. Bozic - Zemun, SERBIA AND MONTENEGRO The course of treatment of refractory metastatic choriocarcinoma treated surgically and with polychemotherapy is presented.  
Fallopian tube carcinoma: incidental finding during surgery for acute pelvic inflammatory disease - case report 526
F. Puig, M. Lapresta, A. Lanzon, R. Crespo - Zaragoza, SPAIN The symptoms of fallopian tube carcinoma are non-specific and often result in misdiagnoses that can lead to delays in treatment.  
Management of a case of primary vaginal cancer with irreducible massive uterine prolapse - a case report 528
A. Karateke, S. Tugrul, Y. Yakut, A. Gürbüz, C. Çam - Istanbul, TURKEY Management of the case of a woman with a huge irreducible uterovaginal prolapse and Stage II vaginal carcinoma is presented.  
Robotic-assisted laparoscopic radical hysterectomy (Piver type III) with pelvic node dissection - case report 531
B.M. Sert, V.M. Abeler - Oslo, NORWAY The first robotic-assisted radical hysterectomy (Piver type III) and bilateral pelvic lymph node dissection for Stage Ib1 cervical carcinoma are described.  
Incidental finding of a malignant peritoneal mesothelioma in an inguinal hernia sac: Report of a case 534
P. Chatzipantelis, E. Kairi-Vassilatou, V. Smyrniotis, A. Pafiti - Athens, GREECE Clinicopathological presentation of a malignant peritoneal mesothelioma in an inguinal hernia sac with emphasis on the differential diagnosis with other malignancies.  
Squamous cell carcinoma arising in a mature cystic teratoma of the ovary with synchronous invasive lobular breast cancer: case report 537
G.M. Filippakis, E.E. Lagoudianakis, M. Genetzakis, P. Antonakis, A. Papadima, A. Boussiotou, V. Katergiannakis, A. Manouras - Athens, GREECE The first report in the literature of a simultaneously occurring squamous cell carcinoma airising in a mature cystic teratoma and invasive lobular carcinoma of the breast is presented.  
 
ERRATA - CORRIGE  
Impact of morbid obesity in surgical management of endometrial cancer: surgical morbidity, clinical and pathological aspects  
S. Erkanli1, F. Kayaselçuk2, T. Bagis1, E. Kus¸çu1 - Adana, TURKEY 1Department of Obstetrics and Gynecology, 2Department of Pathology, Adana (Turkey) Vol. XXVII, n. 4, 2006, page 401

Errata: 1Department of Obstetrics and Gynecology, 2Department of Pathology, Adana (Turkey)
Corrige: 1Department of Obstetrics and Gynecology, 2Department of Pathology, Baskent University School of Medicine, Adana (Turkey)
 
Erratum: A paper by D.C. Dale published in the EJGO 2004, 25, 133-144 entitled “The benefits of haematopoietic growth factors in the management of gynaecological oncology” inadvertently omitted an acknowledgement of editorial assistance of Jackie Williams from Gardiner-Caldwell Communications and whose services were paid for by Amgen Europe.  
 
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
Vol. XXVII, Number 3, 2006
ISSN: 0392-2936
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