Vol. XXXVII, no. 2, 2010 ISSN: 0390-6663


CLINICAL AND EXPERIMENTAL
OBSTETRICS & GYNECOLOGY

an International Journal


Founding Editor
A. Onnis
Montréal (CND)


Editors-in-Chief
M. Marchetti
Montréal (CND)
J.H. Check
Camden, NJ (USA)


Assistant Editor
J. Wilson
San Diego - CA (USA)
Editorial Board
Audet-Lapointe P., Montréal (Canada)
Axt-Fliedner R., Lübeck (Germany)
Basta A., Krakow (Poland)
Bender H.J., Dusseldorf (Germany)
Bhattacharya N., Calcutta (India)
Bonilla Musoles F., Valencia (Spain)
Charkviani T., Tbilisi (Georgia)
Dexeus S., Barcelona (Spain)
Di Paola G., Buenos Aires (Argentina)
Eskes T.K.A.B.,
Nijmegen (The Netherlands)
Franchi M., Verona (Italy)
Friedrich M., Homburg (Germany)
Gomel V., Vancouver (Canada)
Gorins A., Paris (France)
Grella P.V., Padua (Italy)
Holub Z., Kladno (Czech Republic)
Jordan J.A., Birmingham, England (UK)
Kaplan B., Petach Tikva (Israel)
Kralj B., Ljubljana (Slovenia)
Markowska J., Poznan (Poland)
Marth C., Innsbruck (Austria)
Meden-Vrtovec H., Ljubljana (Slovenia)
Ohara N., Kobe (Japan)
Papadopoulos N., Alexandroupolis (Greece)
Rakar S., Ljubljana (Slovenia)
Sciarra J.J., Chicago, IL (USA)
Stelmachow J., Warsaw (Poland)
Varras M.N., Athens (Greece)
Vîrtej P., Bucharest (Romania)
Winter R., Graz (Austria)

Publishing Organization (M. Morsani):
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CLINICAL AND EXPERIMENTAL OBSTETRICS AND GYNECOLOGY (ISSN 0390-6663) publishes original work, preferably brief reports, in the fields of Gynecology, Obstetrics, Fetal Medicine, Gynecological Endocrinology and related subjects. (Fertility and Sterility, Menopause, Uro-gynecology, Ultrasound in Obstetrics and Gynecology, Sexually Transmitted Diseases).The Journal is covered by INDEX MEDICUS, MEDLINE, EMBASE/Excerpta Medica.

CLINICAL AND EXPERIMENTAL OBSTETRICS AND GYNECOLOGY is issued every three months in one volume per year by IROG CANADA Inc. Montréal. Printed in Italy by "La Garangola", Tipografia Editrice - Via E. Dalla Costa, 6 -35129 Padova (Italy).

 

Clinical and Experimental Obstetrics and Gynecology
http://www.irog.net/


General Information

CLINICAL AND EXPERIMENTAL OBSTETRICS AND GYNECOLOGY (ISSN 0390-6663) publishes original peer-reviewed work, preferably brief reports, in the fields of Gynecology, Obstetrics, Fetal Medicine, Gynecological Endocrinology, Fertility and Sterility, Menopause, Uro-gynecology, Ultrasound diagnosis in Obstetrics and Gynecology, Sexually transmitted diseases and related topics. It is indexed in INDEX MEDICUS, MEDLINE, EMBASE/ Excerpta Medica.

AIMS AND SCOPE
Since its inception, the CLINICAL AND EXPERIMENTAL OBSTETRICS AND GYNECOLOGY Journal has had the primary aim to assemble and diffuse scientific researches, particularly original researches, contributions, reviews, and proceedings of meetings in every field of the Discipline.
Today its large diffusion all over the world allows us to collect high quality papers and clinical reports on many interesting studies from every country, even from developing countries. This is the target goal of the Journal – aiming at the diffusion of knowledge and advances in female genital diseases.
This publication tries to cover all aspects of obstetrics and gynecology in an interdisciplinary approach among gynecologists, epidemiologists, pathologists, oncologists, radiologists, microbiologists, surgeons, urologists, neonatologists, genetists and so on.
The first target goal of the Journal is to publish high quality papers in the shortest time possible. Research papers, editorial reviews, case reports, technical notes, book reviews and letters to the Editor are published.

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Papers should be submitted to A. ONNIS Editor-in-Chief of the EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 4900 Côte St. Luc, Apt. 212 MONTREAL, QUÉBEC H3W 2H3 (Canada) - Tel. +514-4893242 - Fax +514-4854513, or Galleria Sto-rione 2/A - 35123 PADOVA (Italy) - Fax +39-049-8752018.

Editorial articles for publication in the "Distinguished Expert Series" should be submitted to P. Bösze, Editor-in-Chief of this section, Department of Gynecology, Saint Stephan Hospital, 1096 Budapest, Nagyvárad tér 1, Telephone (36-1) 275 2172, Fax (36-1)
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© By I.R.O.G. CANADA INC. - Publisher - Editorial office 4900 Côte St. Luc - Apt. 212 - Montréal Québec H3W 2H3 (Canada) - Tel. (514) 4893242-4893640 -Fax (514) 4854513 - Printed in Italy by "La Garangola" - Via E. Dalla Costa, 6 - 35129 Padua (Italy) - Responsible Director: Prof. Antonio Onnis M.D. - Authorization of Padua's Court n. 633 - 28-6-1979
 
Clinical and Experimental Obstetrics & Gynecology - Vol. XXXVII, no. 2, 2010
   
EDITORIAL ARTICLES  
A practical approach to the prevention of miscarriage: part 3 – passive immunotherapy 81
J.H. Check - Camden, NJ (USA)
There is controversy over the efficacy of passive immunotherapy to prevent miscarriage, but there are some data that are
encouraging if the passive immunotherapy is properly given with the right brand and timing.
 
Advantages of using a lower vs higher dosage of gonadotropins for follicular maturation including cycles
of in vitro fertilization-embryo transfer
84
J.H. Check - Camden, NJ (USA)
The use of a lower dosage of exogenous FSH for follicular stimulation can not only save money but may result in higher
pregnancy rates compared to higher dosage regimens.
 
 
REVIEW ARTICLES  
The slow levonorgestrel-releasing intrauterine system (LNG-IUS) 20 mcg/day: a literature review 89
N. Salakos, A. Koumousidis, C. Iavazzo, G. Paltoglou, K. Bakalianou, O. Gregoriou - Athens, GREECE
A review of indications, complications and contraindications of the levonorgestrel-releasing intrauterine system was performed.
 
ORIGINAL ARTICLES  
Reproductive Biology Section  
A novel method to assess the effect of uterine senescence by comparing pregnancy outcome in younger
donors vs older recipients who are sharing a common pool of oocytes
97
J.H. Check, B. Katsoff, T. Jamison, J.K. Choe, D. Brasile, J. Amui - Camden, NJ (USA)
The evaluation of pregnancy and implantation rates aftr transfer of fresh or frozen embryos in younger infertile egg donors vs
older recipients confirmed that the uterus from a woman of advanced reproductive age does not impair embryo implantation.
 
Cryopreservation of blastocysts using a modification of a simplified freezing protocol with a one step
removal of cryoprotectant successfully used previously to freeze 2 pronuclear or multi-cell embryos
99
D. Summers-Chase, J.H. Check, D. Horwath, W. Yuan, K. Swenson, M. Press - Camden, NJ (USA)
A modification of a simplified freezing protocol usd for 2 pronuclear and multi-cell embryos has resulted in a successful cryopreservation
technique for blastocysts.
 
Serum retinol-binding protein-4 levels in polycystic ovary syndrome patients undergoing controlled
ovarian hyperstimulation for in-vitro fertilization cycle
100
R. Orvieto, V. Shuhat, G. Liberty, R. Homburg, E.Y. Anteby, R. Nahum, J. Rabinson, S. Meltcer - Beer
Sheva, ISRAEL
PCOS patients demonstrated a decrease in serum RBP-4 during COH with no correlation to IVF treatment variables or pregnancy
rate.
 
A comparison of pregnancy rates following fresh and frozen embryo transfer according to the use of
leuprolide acetate vs ganirelix vs cetrorelix
105
J.H. Check, C. Wilson, J.K. Choe, J. Amui, B. Katsoff - Camden, NJ (USA)
A retrospective review found that the gonadotropin releasing hormone (GnRH) agonist leuprolide did not result in higher
implantation rates than the GnRH antagonist cetrorelix but both were superior to ganirelix.
 
The effect of endometriosis on pregnancy outcome following in vitro fertilization-embryo transfer (IVFET)
in women with decreased egg reserve
108
J.H. Check, J.R. Liss, J.W. Krotec, J.K. Choe, D. Brasile - Camden, NJ (USA)
The presence of endometriosis did not impair live delivered pregnancy rates following fresh or frozen embryo transfers in
women with diminished egg reserve.
 
Association of the change in serum estradiol (E2) levels from the day of to the day after human chorionic
gonadotropin (hCG) injection and pregnancy outcome following in vitro fertilization-embryo transfer
(IVF-ET) in less than average responders
110
J.H Check, J.K. Choe, J. Amui, D. Brasile - Camden, NJ (USA)
A drop in serum estradiol in a group of women who were less than average responders was not associated with a lower
chance of conception following in vitro fertilization-embryo transfer.
 
General Section  
Effects of tamoxifen on tissue nitrite/nitrate levels and plasma lipid peroxidation in female rats 112
M. Gharehbagni, F. Sendag, F. Akercan, B. Zeybek, E. Sezer, M.C. Terek, N. Karadadas - Izmir, TURKEY
The effects of tamoxifen on lipid peroxidation and oxidant-antioxidant balance were investigated in an animal model.
 
Successful treatment of a female with chronic pseudo-intestinal obstruction with sympathomimetic
amines and thyroid hormone replacement
115
J.H. Check, R. Cohen - Camden, NJ (USA)
Another way that idiopathic orthostatic edema may present is with classic symptoms and signs of chronic pseudointestinal
obstruction, and similar to other associated pain syndromes, the condition responds to sympathomimetic amine treatment.
 
Emergency obstetric hysterectomy at two tertiary centers: a clinical analysis of 11 years experience 117
M. Varras, Ch. Akrivis, Ch. Plis, G. Tsoukalos - Ioannina, GREECE
The incidence, indications and maternal mortality of emergency obstetric hysterectomies to control major postpartum hemorrhage
after delivery following a pregnancy of at least 24 weeks’ gestation, regardless of the mode of delivery, at two tertiary
Greek hospitals are presented.
 
Comparision of reproductive outcome of the women with hypogonadotropic hypogonadism and tubal
factor infertility
120
G. Yildirim, C. Ficicioglu, R. Attar, O. Akcin, N. Tecellioglu - Istanbul, TURKEY
The outcome of women with hypogonadotropic hypogonadism undergoing assisted reproductive treatment are comparable to
women with tubal factor infertility.
 
Effect of long-time administration of tibolone on vaginal cytology of castrated rats 123

H.N. Henriques, A.C. Bergmann de Carvalho, J.A.S. Pantaleão, M.A. Guzmán-Silva - Niteroi, RJ BRAZIL
Tibolone administered at high-dose and long-term has estrogenic effects in vaginal epithelium evident after one dose, without
changes over time.

 
Vaginal fluid pH, cervicovaginitis and cervical length in pregnancy 127
F. Sendag, M. Kazandi, F. Akercan, A.C. Kazandi, N. Karadadas, S. Sagol - Irbid, JORDAN
Elevated vaginal fluid pH in women at 16-22 weeks of gestation seems to be associated with decreased cervical length and
increased risk of preterm delivery.
 
Perineal ultrasound evaluation of urethral mobility after the TVT-O procedure 131
L. Di Pietto, C. Scaffa, A. Lambiase, M. Torella, C. Sciorio, E. Dato, A. Nocerino, M.L. Di Petrillo, R.
Fusco, M. Rotondi, E.M. Messalli, N. Colacurci - Naples, ITALY
By means of perineal ultrasound the study evaluates urethral mobility in urinary stress incontinence before and after transobturator
tension-free vaginal tape surgery.
 
Is placebo as effective as estrogen regimens on vasomotor symptoms in women with surgical menopause? 135
H. Hassa, H.M. Tanir, T. Oge - Agri, TURKEY
Oral and transdermal forms of estrogen and placebo improved total Greene Climacteric Scale scores in women with surgical
menopause.
 
Tubal ectopic pregnancy in the north of Jordan: presentation and management 138
B. Obeidat, F. Zayed, Z. Amarin, N. Obeidat, M.F. El-Jallad - Irbid, JORDAN
A retrospective study of the approach to the management tubal ectopic pregnancy in the north of Jordan.
 
Umbilical cord prolapse in the southeast region of Turkey: evaluation of 79 cases 141
M. Erdemoglu, A. Kale, U. Kuyumcuoglu, N. Akdeniz, A.I. Güzel - Diyarbakir, TURKEY
Fetal weight ≤ 2500 and abnormal fetal presentation is associated with increased risk of umbilical cord prolapse. Cesarean section
decreases the risk of perinatal mortality.
 
Adolescent pregnancies and obstetric outcomes in Southeast Turkey: data from two regional centers 144
D.C. Arıkan, M. Kaplanog˘lu, H. Kıran, A. Özer, A. Cos¸kun, E. Turgut - Istanbul, TURKEY
The incidence of adolescent pregnancy is still high in Turkey. Preterm labor, intrauterine growth retardation, and stillbirth were
significantly higher in pregnant adolescents.
 
Pregnancy-related acute renal failure in the southeast region of Turkey: analysis of 75 cases 148
M. Erdemog˘lu, U. Kuyumcuog˘lu, A. Kale, N. Akdeniz - Diyarbakir, TURKEY
A case series of 75 patients affected by acute renal failure related with pregnancy in a limited region of Turkey is reported.
 
An analysis of hysteroscopy experience over a seven-year period 150
E. Ozturk, M.G. Ugur, O. Balat, I. Kutlar, E. Dikensoy, B. Cebesoy - Gaziantep, TURKEY
Analysis of hysteroscopy experience indicates that this method is safe and useful for various gynecological disorders.
 
Is insulin-dependent diabetes and obesity a predisposition for endometrial and pancreatic carcinoma? 152
M. Gojnic, V. Dugalic, M. Brankovic, I. Stojanovic, M. Acimovic, B. Vasiljevic - Belgrade, SERBIA
The same risk factors for endometrial adenocarcinoma may also apply for pancreatic adenocarcinoma.
 
CASE REPORTS  
Peripartum cardiomyopathy and Klippel-Trenaunay syndrome 155
G. Carta, V. De Lellis, M. Di Nicola, D. Kaliakoudas - L’Aquila, ITALY
This study illustrates the correlation between the KTS and PPCM in women with twin pregnancies.
 
Novel therapeutic strategy for uterine arteriovenous fistulas: case report 158
R. Kizaki, J. Fujimoto, E. Sato, T. Tamaya - Gifu City, JAPAN
Precise evaluation with color Doppler, CT and angiography led to an adequate therapeutic strategy for uterine arteriovenous fistulas.
 
Book Review 161